Beginning with high quality 135lb Italian paper and miscellaneous paint brushes, I lay initial acrylic washes of colour using my left hand. It is not my dominant arm, but its strength is more reliable than the other.
My right hand has more keen dexterity. I've figured it out that I can save mental energy for detail work by using my left hand for the "less important" steps in building images. Then, I work more rapidly with my dominant but neurologically-limited right arm, and a pallet knife.
It is really difficult to explain the complexity of how Multiple Sclerosis truly affects me, but I'm persevering and finding ways around obstacles day after day. When you need to make art, you find a way.